MATRON

Maternal Audit on ThRmbosis Outcome and decisioN

Update

MATRON was presented at BSH 2026 as top abstract oral presentation. It will also be presented at ISTH 2026 as oral presentation.

• Manuscript has been submitted

• Currently, we are working on MATRON international and prospective studies. Contact either Giulia Simini - giulia.simini@nhs.net or Laura Yeates (laura.yeates1@nhs.net)

Publications
Paper on survey: Physician Survey on the Management of Pulmonary Embolism in Pregnancy: Need for Guidance and Training. https://onlinelibrary.wiley.com/doi/10.1002/jha2.70113

Abstract: Physician Survey on the Management of Pulmonary Embolism in Pregnancy: Need for Guidance and Training. https://library.ehaweb.org/eha/2024/eha2024-congress/420374/giulia.simini.physician.survey.on.management.of.pulmonary.embolism.in.html

A pan-UK audit aiming to assess management of high risk and intermediate-high risk pulmonary embolism in pregnancy and puerperium. Archive documents from the audit below, for information.

1. Register your interest with study lead, Giulia Simini - giulia.simini@nhs.net

2. Start the audit process approval in your trust using the info on the audit template form - Clinical Audit Proposal Form

3. Complete this online form so we can give you access to RedCAP (for data collection):  https://redcap.link/gmy477gc  

Please click here for the full study protocol

Lay Summary

Blood clots in the lungs, or pulmonary embolism (PE) are a leading cause of death in pregnancy and after childbirth. This national audit will review how high-risk PE is treated in pregnant and recently pregnant women across the UK, and how these treatments affect mothers and babies, to help improve care and outcomes.
A paper on this was published in 2025, and further analysis is being carried out.